Current Projects

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Spatial Metabolomic Mapping of Long COVID Tissues Using MALDI Mass Spectrometry Imaging

Project SummaryThis project applies matrix-assisted laser desorption/ionization mass spectrometry imaging (MALDI MSI) to identify molecular changes within tissues from people with...

Urinary Extracellular Vesicle Profiling to Identify Borrelia-Associated Neuroimmune Subtypes in Long COVID

Project SummaryThis project uses urinary extracellular vesicles (uEVs) as a noninvasive platform to detect microbial and host-derived signals in Long COVID,...

Decoding Viral Persistence Signals in Biofluids Using Single-Particle EVP Analysis

Project SummaryThis project investigates extracellular vesicles and particles (EVPs) as carriers of viral and host-derived signals that may drive Long COVID....

Infection-Triggered Neurodegeneration in Long COVID: Retinal Biomarkers and Organoid Models for Mechanism and Therapy

Project SummaryThis project investigates infection-triggered neurodegenerative protein aggregation as a potential driver of neurological symptoms in Long COVID. It focuses on...

Development of advanced diagnostics to identify the Babesia parasite

Project Summary:To develop novel enrichment culture, serological, and visualization methods for the diagnosis of the parasite Babesia in people with a...

Microfluidic capture to identify potential viral particles in Long COVID blood

Project Summary:To analyze Long COVID blood samples with a novel microfluidic technology that isolates rare, intact SARS-CoV-2 viral particles from complex...

MENSA virus “immune snapshot” testing to identify Long COVID clinical trial responders

Project Summary: A project to add MENSA testing to measure virus-specific plasmablast “immune snapshots” to a clinical trial at the Mount...

Characterization of the vagus nerve microbiome & virome

Project Summary: To use unbiased next generation metagenomic sequencing to characterize the healthy vagus nerve microbiome/virome. Vagus nerve tissue samples analyzed for...

Validation of a Cytomegalovirus-based biomarker for Alzheimer’s disease

Project Summary:A project to validate a blood-based biomarker capable of reflecting the presence of activated microglia neuroimmune cells and Cytomegalovirus infection...

Long COVID low-dose rapamycin clinical trial

Project Summary: A double blinded randomized controlled pilot clinical trial to determine if low-dose rapamycin can improve symptoms in patients with...

Expansion of LIINC collaborative study to ME/CFS

Project Summary: To use advanced technologies to study critically important – yet understudied – biological factors in ME/CFS patients whose illness...

Digital transcriptomics to capture SARS-CoV-2 persistence in blood

Project Summary:A project to further validate findings from a long COVID study that identified SARS-CoV-2 RNA transcripts in long COVID blood...

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